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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN7103 | 13,21-Dihydroeurycomanone | Pasakbumin C | Anti-infection , Parasite |
13,21-Dihydroeurycomanone (Pasakbumin C) is a natural product isolated from the root of Eurycoma longifolia with antiparasitic activity such as Plasmodium falciparum and Toxoplasma gondii. | |||
T1172 | Diclazuril | R-64433 | Antibiotic , Parasite |
Diclazuril (R-64433) is a coccidiostat. | |||
T36692 | Fanotaprim | DHFR | |
Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor. Fanotaprim inhibits the growth of T. gondii strains with a TgDHFR IC50 of 1.57 ± 0.11 nM and a hDHFR IC50 of 308 ± 71 nM and a hDHFR to TgDHFR selectivity ratio o... | |||
T72081 | CpCDPK1/TgCDPK1-IN-2 | Parasite | |
CpCDPK1/TgCDPK1-IN-2 is a dual inhibitor of CpCDPK1 and TgCDPK1 with IC50 values of 12 and 5 nM for CpCDPK1 and TgCDPK1, respectively.CpCDPK1/TgCDPK1-IN-2 can be used in the study of diseases associated with infection of... | |||
T0819 | Spiramycin | Espiramicin,Sequamycin,Rovamycin,Provamycin,Formacidine | Antibacterial , Antibiotic , Parasite |
Spiramycin (Rovamycin) is a macrolide antibiotic produced by Streptomyces ambofaciens. The drug is effective against gram-positive aerobic pathogens, N. gonorrhoeae, and staphylococci. It is used to treat infections caus... | |||
T29003 | TRC-19 | ||
TRC-19 is a potent and selective inhibitor of Toxoplasma gondii dihydrofolate reductase. TRC-19 shows an IC50 of 9 nM and 89-fold selectivity in favor of Toxoplasma gondii dihydrofolate reductase. | |||
T61671 | MMV687807 | ||
MMV687807 is a potent anthelmintic compound exhibiting strong efficacy against Toxoplasma gondii (T. gondii). It demonstrates an IC50 value of 0.15 μM and a CC50 value of 1.69 μM [1]. | |||
T69311 | GW300657X | ||
GW300657X is a small molecule inhibitor that blocks toxoplasma gondii rhoptry kinase 18 and maintains moderate CDK2-cyclin A inhibitory activity. | |||
T76121 | Phosphoglucomutase | Endogenous Metabolite | |
Phosphoglucomutase promotes cyst development in Toxoplasma gondii. Deficiency of Phosphoglucomutase causes metabolic disorders. | |||
T38269 | Purfalcamine | ||
Purfalcamine is an orally active, selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor with an IC50 of 17 nM and an EC50 of 230 nM. Purfalcamine has antimalarial activity and causes mala... | |||
T35750 | Trypacidin | ||
Trypacidin is a fungal metabolite originally isolated fromA. fumigatus.1It is active againstB. subtilisandM. bovis(MICs = 12.5 and 1.25 μg/ml, respectively), as well asT. cruziandT. gondii(MICs = 5-10 and 10-20 μg/ml, re... |